HL-A antigens of 70 leprosy patients and 40 normal healthy individuals were determined by the standard microlymphocytotoxicity test. Both lepromatous and non-lepromatous leprosy patients were tested for the presence of 11 HL-A antigens, and the frequency of each specificity was compared with that in a normal population of the same ethnic group. Although the statistical significance of HL-A8 specificity was found to be marginal in lepromatous leprosy patients, when using ordinary 2 times 2 statistics, there did seem to be a decreased frequency of HL-A9 among the non-lepromatous type. Other antigens tested did not reveal any significant differences between the two groups of subjects.
BT - Tissue antigens C1 - http://www.ncbi.nlm.nih.gov/pubmed/1129752?dopt=Abstract DA - 1975 Apr DO - 10.1111/j.1399-0039.1975.tb00534.x IS - 2 J2 - Tissue Antigens LA - eng N2 -HL-A antigens of 70 leprosy patients and 40 normal healthy individuals were determined by the standard microlymphocytotoxicity test. Both lepromatous and non-lepromatous leprosy patients were tested for the presence of 11 HL-A antigens, and the frequency of each specificity was compared with that in a normal population of the same ethnic group. Although the statistical significance of HL-A8 specificity was found to be marginal in lepromatous leprosy patients, when using ordinary 2 times 2 statistics, there did seem to be a decreased frequency of HL-A9 among the non-lepromatous type. Other antigens tested did not reveal any significant differences between the two groups of subjects.
PY - 1975 SP - 85 EP - 7 T2 - Tissue antigens TI - Histocompatibility antigens (HL-A) in leprosy. VL - 5 SN - 0001-2815 ER -