TY - JOUR
KW - Adenosine Triphosphate
KW - Animals
KW - Foot
KW - Humans
KW - Leprostatic Agents
KW - leprosy
KW - Luminescent Measurements
KW - Mice
KW - Mycobacterium leprae
KW - Treatment Outcome
AU - Gupta U D
AU - Katoch K
AU - Singh H B
AU - Natrajan M
AU - Sharma V D
AU - Katoch V M
AB - <p>The therapeutic effect of a drug regimen of conventional drugs as well as newer drugs like ofloxacin and minocycline in smear-positive multibacillary (MB) leprosy cases was assessed by mouse foot-pad and ATP bioluminiscence methods. Biopsies were taken before starting treatment and after one year of treatment. They were processed for viability assessment by normal mouse foot-pad inoculation and bacillary ATP assay techniques. The test regimen was quite effective in its anti-bacterial effect as it was found to result in loss of bacillary viability in all the cases, as assessed by both methods.</p>
BT - Indian journal of leprosy
C1 - http://www.ncbi.nlm.nih.gov/pubmed/11212477?dopt=Abstract
CN - Infolep Library - available
DA - 2000 Oct-Dec
IS - 4
J2 - Indian J Lepr
LA - eng
N2 - <p>The therapeutic effect of a drug regimen of conventional drugs as well as newer drugs like ofloxacin and minocycline in smear-positive multibacillary (MB) leprosy cases was assessed by mouse foot-pad and ATP bioluminiscence methods. Biopsies were taken before starting treatment and after one year of treatment. They were processed for viability assessment by normal mouse foot-pad inoculation and bacillary ATP assay techniques. The test regimen was quite effective in its anti-bacterial effect as it was found to result in loss of bacillary viability in all the cases, as assessed by both methods.</p>
PY - 2000
SP - 437
EP - 42
T2 - Indian journal of leprosy
TI - Assessment of viability by normal mouse foot-pad and bacillary ATP bioluminescence assay in multibacillary cases treated with an MDT regimen using conventional as well as newer drugs like minocycline and ofloxacin.
VL - 72
SN - 0254-9395
ER -