TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Anti-Bacterial Agents KW - Bacteria KW - Bacterial Infections KW - Child KW - Diabetes Complications KW - Female KW - Foot Ulcer KW - Gentamicins KW - Humans KW - leprosy KW - Male KW - Middle Aged KW - Penicillins KW - Retrospective Studies KW - Suppuration AU - Ebenezer G AU - Daniel S AU - Suneetha S AU - Reuben E AU - Partheebarajan S AU - Solomon S AB -

In this retrospective study, sensitivity of organisms cultured from ulcers of leprosy patients without and with diabetes mellitus, diabetic patients without leprosy and patients with ulcers from other causes was examined. The profile of organisms grown from these groups of patients did not differ significantly. However, there was a high prevalence of organisms like Proteus, E. coli and Enterococcus in the ulcers of leprosy patients indicating faecal contamination of the ulcers. Co-trimaxazole and tetracycline were of little value in the treatment of these ulcers. We therefore recommend that in situations where there is no culture facility, the patients be started on a course of penicillin and gentamycin. If these antibiotics fail, it would be necessary to use more advanced antibiotics like norfloxacin, amikacin and ciprofloxacin.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/11212478?dopt=Abstract CN - Infolep Library - available DA - 2000 Oct-Dec IS - 4 J2 - Indian J Lepr LA - eng N2 -

In this retrospective study, sensitivity of organisms cultured from ulcers of leprosy patients without and with diabetes mellitus, diabetic patients without leprosy and patients with ulcers from other causes was examined. The profile of organisms grown from these groups of patients did not differ significantly. However, there was a high prevalence of organisms like Proteus, E. coli and Enterococcus in the ulcers of leprosy patients indicating faecal contamination of the ulcers. Co-trimaxazole and tetracycline were of little value in the treatment of these ulcers. We therefore recommend that in situations where there is no culture facility, the patients be started on a course of penicillin and gentamycin. If these antibiotics fail, it would be necessary to use more advanced antibiotics like norfloxacin, amikacin and ciprofloxacin.

PY - 2000 SP - 443 EP - 9 T2 - Indian journal of leprosy TI - Bacteriological study of pus isolates from neuropathic plantar ulcers associated with acute inflammatory phase. VL - 72 SN - 0254-9395 ER -