Thalidomide is the treatment of choice for severe or recurrent erythema nodosum leprosum. Its use has been associated with deep vein thrombosis in patients with blood disorders, however, particularly when used in combination with corticosteroids or chemotherapy. We describe a case of deep vein thrombosis in a 43-year-old man with lepromatous leprosy who was being treated with thalidomide and prednisone for a type 2 leprosy reaction (erythema nodosum leprosum); the patient also had transiently positive antiphospholipid antibody results. We stress the importance of considering deep vein thrombosis, a potentially fatal complication, in dermatology patients treated with thalidomide.
BT - Actas dermo-sifiliográficas C1 -http://www.ncbi.nlm.nih.gov/pubmed/22705284?dopt=Abstract
CN - PETITI MARTIN 2012 DA - 2012 Jun 15 LA - eng N2 -Thalidomide is the treatment of choice for severe or recurrent erythema nodosum leprosum. Its use has been associated with deep vein thrombosis in patients with blood disorders, however, particularly when used in combination with corticosteroids or chemotherapy. We describe a case of deep vein thrombosis in a 43-year-old man with lepromatous leprosy who was being treated with thalidomide and prednisone for a type 2 leprosy reaction (erythema nodosum leprosum); the patient also had transiently positive antiphospholipid antibody results. We stress the importance of considering deep vein thrombosis, a potentially fatal complication, in dermatology patients treated with thalidomide.
PY - 2012 T2 - Actas dermo-sifiliográficas TI - Deep Vein Thrombosis in a Patient With Lepromatous Leprosy Receiving Thalidomide to Treat Leprosy Reaction. UR - http://www.gefaesse.at/download/12_aktuelle_literatur-17-04-2012/Deep-venous-thrombosis-and-pulmonary-embolism-secondary-to-co-administration-of-thalidomide-and-oral---.pdf SN - 1578-2190 ER -