Two cases of relapse in borderline leprosy were reported. Despite the late-reversal, reaction-like feature, the suspicion of relapse in both was based on persistent and slow-developing skin lesions and an absence of acute neuritis or reaction during one year of follow-up. The authors have considered this possible occurrence in lepromatous borderline-treated patients after their immune cellular restoration and defend that not all Type 1 reactions would be an inflammatory answer to persistent Mycobacterium leprae, but that they could be. Therefore, a relapse diagnosis could be applied and it is more advisable, as one year of Multi-Drug Therapy (MDT) is less dangerous and more efficient for these cases than one year of corticosteroids.
BT - Revista do Instituto de Medicina Tropical de Sao Paulo C1 - http://www.ncbi.nlm.nih.gov/pubmed/22183459?dopt=Abstract C2 - Brazil C6 - http://dx.doi.org/10.1590/S0036-46652011000600008 CY - Sao Paulo DA - 2011 Nov-Dec DO - 10.1590/s0036-46652011000600008 IS - 6 J2 - Rev. Inst. Med. Trop. Sao Paulo LA - eng N2 -Two cases of relapse in borderline leprosy were reported. Despite the late-reversal, reaction-like feature, the suspicion of relapse in both was based on persistent and slow-developing skin lesions and an absence of acute neuritis or reaction during one year of follow-up. The authors have considered this possible occurrence in lepromatous borderline-treated patients after their immune cellular restoration and defend that not all Type 1 reactions would be an inflammatory answer to persistent Mycobacterium leprae, but that they could be. Therefore, a relapse diagnosis could be applied and it is more advisable, as one year of Multi-Drug Therapy (MDT) is less dangerous and more efficient for these cases than one year of corticosteroids.
PB - Scielo PP - Sao Paulo PY - 2011 SP - 341 EP - 3 T2 - Revista do Instituto de Medicina Tropical de Sao Paulo TI - Early diagnosis of relapse in borderline leprosy: two case reports. TT - Diagnóstico precoce de recidiva em hanseníase dimorfa: apresentação de dois casos UR - http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652011000600008&lng=en&nrm=iso&tlng=en VL - 53 SN - 1678-9946 ER -