TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - C-Reactive Protein KW - Case-Control Studies KW - Female KW - Humans KW - Interferon-gamma KW - leprosy KW - Male KW - Middle Aged KW - Periodontal Diseases KW - Stomatognathic Diseases KW - Young Adult AU - Motta ACF AU - Furini RB AU - Simão JCL AU - Vieira MB AU - Ferreira MAN AU - Komesu MC AU - Foss N AB -
INTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection.
METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after elimination of the foci of infection.
RESULTS: Group I presented more reactions than group II did, and improvement of the reactions after dental treatment. Serum CRP and IP-10 did not differ before and after the dental treatment, but differed between the groups.
CONCLUSIONS: Oral infection could be an exacerbating factor in leprosy reactions.
BT - Revista da Sociedade Brasileira de Medicina Tropical C1 - http://www.ncbi.nlm.nih.gov/pubmed/22031082?dopt=Abstract C2 - Brazil CY - Rio De Janeiro DA - 2011 Oct DO - 10.1590/s0037-86822011000500022 IS - 5 J2 - Rev. Soc. Bras. Med. Trop. LA - eng N2 -INTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection.
METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after elimination of the foci of infection.
RESULTS: Group I presented more reactions than group II did, and improvement of the reactions after dental treatment. Serum CRP and IP-10 did not differ before and after the dental treatment, but differed between the groups.
CONCLUSIONS: Oral infection could be an exacerbating factor in leprosy reactions.
PB - Scielo PP - Rio De Janeiro PY - 2011 SP - 633 EP - 5 T2 - Revista da Sociedade Brasileira de Medicina Tropical TI - Could leprosy reaction episodes be exacerbated by oral infections? UR - http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000500022&nrm=iso VL - 44 SN - 1678-9849 ER -