TY - JOUR
KW - Adult
KW - Brazil
KW - Cohort Studies
KW - Female
KW - Hematuria
KW - Humans
KW - Kidney Diseases
KW - Kidney Function Tests
KW - Leprosy, Multibacillary
KW - Leprosy, Paucibacillary
KW - Male
KW - Middle Aged
KW - Proteinuria
KW - Risk Factors
KW - Young Adult
AU - Daher E
AU - Silva G
AU - Cezar L
AU - Lima R
AU - Gurjão N
AU - Mota R
AU - Abreu KLS
AU - Rocha N
AU - Oliveira M
AU - Libório A
AB - <p>We investigated the factors associated with renal dysfunction in leprosy patients from Brazil. We report on a historical cohort of leprosy patients followed in two hospitals in Fortaleza City in northeastern Brazil. The factors associated with renal dysfunction were investigated. A total of 923 patients were included, with a mean age of 41.5 ± 19.1 years, and 53.3% were male. Renal dysfunction was found in 35 cases (3.8%). Proteinuria was found in 4.8% of cases, haematuria in 6.8% and leukocyturia in 10.4%. Factors associated with renal dysfunction by multivariate analysis were: reaction episode (odds ratio [OR] = 3.9, P = 0.03), multibacillary classification (OR = 3.5, P = 0.02) and advanced age (OR = 1.04, P = 0.01). Four patients (0.4%) died. Leprosy is associated with renal dysfunction, especially in older patients and those presenting with reaction episode and multibacillary classification.</p>
BT - Tropical doctor
C1 - http://www.ncbi.nlm.nih.gov/pubmed/21532002?dopt=Abstract
CN - DAHER 2011
DA - 2011 Jul
DO - 10.1258/td.2011.100436
IS - 3
J2 - Trop Doct
LA - eng
N2 - <p>We investigated the factors associated with renal dysfunction in leprosy patients from Brazil. We report on a historical cohort of leprosy patients followed in two hospitals in Fortaleza City in northeastern Brazil. The factors associated with renal dysfunction were investigated. A total of 923 patients were included, with a mean age of 41.5 ± 19.1 years, and 53.3% were male. Renal dysfunction was found in 35 cases (3.8%). Proteinuria was found in 4.8% of cases, haematuria in 6.8% and leukocyturia in 10.4%. Factors associated with renal dysfunction by multivariate analysis were: reaction episode (odds ratio [OR] = 3.9, P = 0.03), multibacillary classification (OR = 3.5, P = 0.02) and advanced age (OR = 1.04, P = 0.01). Four patients (0.4%) died. Leprosy is associated with renal dysfunction, especially in older patients and those presenting with reaction episode and multibacillary classification.</p>
PY - 2011
SP - 148
EP - 50
T2 - Tropical doctor
TI - Renal dysfunction in leprosy: a historical cohort of 923 patients in Brazil.
UR - http://tdo.sagepub.com/content/41/3/148.full.pdf+html
VL - 41
SN - 1758-1133
ER -