TY - JOUR KW - Brazil KW - Gene Frequency KW - Genetic Predisposition to Disease KW - Humans KW - Interferon-gamma KW - leprosy KW - Microsatellite Repeats KW - Monte Carlo Method AU - Reynard M P AU - Turner D AU - Junqueira-Kipnis A P AU - Ramos de Souza M AU - Moreno C AU - Navarrete C V AB -

A group of Brazilian leprosy patients and controls were genotyped for a CA-repeat microsatellite polymorphism within the interferon (IFN)-gamma gene. A significantly higher frequency of alleles 5-7 was observed in this patient population, indicating that IFN-gamma gene polymorphism may contribute to the course of leprosy post-infection.

BT - European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics C1 - http://www.ncbi.nlm.nih.gov/pubmed/12648284?dopt=Abstract DA - 2003 Apr IS - 2 J2 - Eur. J. Immunogenet. LA - eng N2 -

A group of Brazilian leprosy patients and controls were genotyped for a CA-repeat microsatellite polymorphism within the interferon (IFN)-gamma gene. A significantly higher frequency of alleles 5-7 was observed in this patient population, indicating that IFN-gamma gene polymorphism may contribute to the course of leprosy post-infection.

PY - 2003 SP - 149 EP - 51 T2 - European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics TI - Allele frequencies for an interferon-gamma microsatellite in a population of Brazilian leprosy patients. VL - 30 SN - 0960-7420 ER -