TY - JOUR
KW - Animals
KW - Antigens, Bacterial
KW - Glycolipids
KW - Humans
KW - leprosy
KW - Mycobacterium leprae
KW - Schwann Cells
AU - Young D B
AB - <p>A recent study has demonstrated that the species-specific phenolic glycolipid of Mycobacterium leprae triggers uptake into Schwann cells by interaction with laminin-2 and the alpha-dystroglycan receptor. This finding emphasizes the importance of lipids in the biology of mycobacterial infection and suggests possible strategies to combat nerve damage in leprosy.</p>
BT - Trends in microbiology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/11173227?dopt=Abstract
DA - 2001 Feb
DO - 10.1016/s0966-842x(00)01917-x
IS - 2
J2 - Trends Microbiol.
LA - eng
N2 - <p>A recent study has demonstrated that the species-specific phenolic glycolipid of Mycobacterium leprae triggers uptake into Schwann cells by interaction with laminin-2 and the alpha-dystroglycan receptor. This finding emphasizes the importance of lipids in the biology of mycobacterial infection and suggests possible strategies to combat nerve damage in leprosy.</p>
PY - 2001
SP - 52
EP - 4
T2 - Trends in microbiology
TI - Leprosy lipid provides the key to Schwann cell entry.
VL - 9
SN - 0966-842X
ER -