TY - JOUR
KW - Adjuvants, Immunologic
KW - Cancer Vaccines
KW - GTP Phosphohydrolases
KW - Humans
KW - leprosy
KW - Malaria Vaccines
KW - Merozoite Surface Protein 1
KW - Mycobacterium bovis
KW - Recombinant Proteins
KW - Tuberculosis
KW - Urinary Bladder Neoplasms
AU - Yamada T
AB - <p>The progress of study on recombinant BCG was stated briefly. And then our studies on recombinant BCG were mentioned. Recombinant BCG secreting alpha antigen-fused merozoite surface protein 1 (MSP 1) was prepared and tested for its ability to control infections of Plasmodium yoelii. Result turned out it controlled the infection better than recombinant MSP 1 mixed with Freund incomplete adjuvant did. Recombinant BCG secreting excess amounts of antigen 85 complex A controlled infection of Mycobacterium leprae. Addition of recombinant BCG secreting alpha antigen-fused IL-2 to peritoneal exudate cells induced IFN-gamma resulting in killing bladder cancer cells more efficiently than parental BCG did.</p>
BT - Kekkaku : [Tuberculosis]
C1 - http://www.ncbi.nlm.nih.gov/pubmed/11004802?dopt=Abstract
DA - 2000 Aug
IS - 8
J2 - Kekkaku
LA - jpn
N2 - <p>The progress of study on recombinant BCG was stated briefly. And then our studies on recombinant BCG were mentioned. Recombinant BCG secreting alpha antigen-fused merozoite surface protein 1 (MSP 1) was prepared and tested for its ability to control infections of Plasmodium yoelii. Result turned out it controlled the infection better than recombinant MSP 1 mixed with Freund incomplete adjuvant did. Recombinant BCG secreting excess amounts of antigen 85 complex A controlled infection of Mycobacterium leprae. Addition of recombinant BCG secreting alpha antigen-fused IL-2 to peritoneal exudate cells induced IFN-gamma resulting in killing bladder cancer cells more efficiently than parental BCG did.</p>
PY - 2000
SP - 517
EP - 20
T2 - Kekkaku : [Tuberculosis]
TI - [Study on recombinant BCG].
VL - 75
SN - 0022-9776
ER -