TY - JOUR KW - Age Factors KW - Animals KW - Basophils KW - Blood Chemical Analysis KW - Disease Models, Animal KW - Histiocytes KW - leprosy KW - Leukocytes KW - Lymph Nodes KW - Lymphocytes KW - Lymphoid Tissue KW - Mycobacterium leprae KW - Neutrophils KW - Spleen KW - Thymus Gland KW - Xenarthra AU - Purtilo D T AU - Walsh G P AU - Storrs E E AU - Gannon C AB -

The armadillo is rapidly emerging as an animal for biomedical research. A morphological study of the immune system of the armadillo was undertaken to try to demonstrate a possible defect in the morphogenesis of the lymphoid organs that could account for their susceptibility to leprosy. Blood from 20 domesticated adult armadillos revealed lymphocytes predominated among circulating leukocytes in the majority of animals, whereas in wild animals neutrophils predominated. Necropsies revealed well-developed thymus glands and the thymus-dependent areas in lymph nodes and spleens contained abundant lymphoid cells. Hence, we conclude that the susceptibility of the armadillo to leprosy cannot be explained on a morphological basis.

BT - The Anatomical record C1 - http://www.ncbi.nlm.nih.gov/pubmed/1091181?dopt=Abstract DA - 1975 Apr DO - 10.1002/ar.1091810405 IS - 4 J2 - Anat. Rec. LA - eng N2 -

The armadillo is rapidly emerging as an animal for biomedical research. A morphological study of the immune system of the armadillo was undertaken to try to demonstrate a possible defect in the morphogenesis of the lymphoid organs that could account for their susceptibility to leprosy. Blood from 20 domesticated adult armadillos revealed lymphocytes predominated among circulating leukocytes in the majority of animals, whereas in wild animals neutrophils predominated. Necropsies revealed well-developed thymus glands and the thymus-dependent areas in lymph nodes and spleens contained abundant lymphoid cells. Hence, we conclude that the susceptibility of the armadillo to leprosy cannot be explained on a morphological basis.

PY - 1975 SP - 725 EP - 33 T2 - The Anatomical record TI - The immune system of the nine-banded armadillo (Dasypus novemcinctus, Linn). VL - 181 SN - 0003-276X ER -