TY - JOUR
KW - Animals
KW - Humans
KW - leprosy
KW - Macrophages, Peritoneal
KW - Mice
KW - Mice, Knockout
KW - Nitric Oxide Synthase
KW - Nitric Oxide Synthase Type II
AU - Adams L B
AU - Job C K
AU - Krahenbuhl J L
AB - <p>The manifestation of leprosy in humans is largely determined by host immunity to Mycobacterium leprae and is a model for immunoregulation in a human disease. However, animal models available for exploration of the leprosy spectrum are inadequate. This study explored M. leprae infection in mice deficient in inducible nitric oxide synthase, and this report describes elements resembling borderline tuberculoid leprosy in humans.</p>
BT - Infection and immunity
C1 - http://www.ncbi.nlm.nih.gov/pubmed/10948185?dopt=Abstract
DA - 2000 Sep
DO - 10.1128/iai.68.9.5462-5465.2000
IS - 9
J2 - Infect. Immun.
LA - eng
N2 - <p>The manifestation of leprosy in humans is largely determined by host immunity to Mycobacterium leprae and is a model for immunoregulation in a human disease. However, animal models available for exploration of the leprosy spectrum are inadequate. This study explored M. leprae infection in mice deficient in inducible nitric oxide synthase, and this report describes elements resembling borderline tuberculoid leprosy in humans.</p>
PY - 2000
SP - 5462
EP - 5
T2 - Infection and immunity
TI - Role of inducible nitric oxide synthase in resistance to Mycobacterium leprae in mice.
UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101819/pdf/ii005462.pdf
VL - 68
SN - 0019-9567
ER -