More than two decades ago, when HIV was first detected, many investigators predicted the rise of leprosy secondary to opportunistic infection. Recently the phenommenon of immune reconstitution inflammatory syndrome (IRIS), or leprosy reversal respons, has received attraction. IRIS often occurs secondary to initiating highly active antiretroviral therapy (HAART). The first indications of an interaction between HIV an Mycobacterium leprae occurred only recently, with the identification of IRIS after initiation of HAART in patients with HIV and previously undetected leprosy.
BT - Emerging Infectious Diseases C1 -http://www.ncbi.nlm.nih.gov/pubmed/18252138
CN - MARTINIUK 2007A DA - 2007/09// IS - 9 J2 - Emerg Infect Dis. LA - eng N2 -
More than two decades ago, when HIV was first detected, many investigators predicted the rise of leprosy secondary to opportunistic infection. Recently the phenommenon of immune reconstitution inflammatory syndrome (IRIS), or leprosy reversal respons, has received attraction. IRIS often occurs secondary to initiating highly active antiretroviral therapy (HAART). The first indications of an interaction between HIV an Mycobacterium leprae occurred only recently, with the identification of IRIS after initiation of HAART in patients with HIV and previously undetected leprosy.
PY - 2007 SP - 1438 EP - 1440 T2 - Emerging Infectious Diseases TI - Leprosy as Immune Reconstitution Inflammatory Syndrome in HIV-positive persons : letter to the editor UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857291/pdf/07-0301_finalL.pdf VL - 13 ER -