TY - JOUR
KW - Adult
KW - Aged
KW - Anti-Infective Agents, Local
KW - Child
KW - Combined Modality Therapy
KW - Drug Resistance, Microbial
KW - Female
KW - Foot Ulcer
KW - Gram-Negative Bacterial Infections
KW - Humans
KW - Immobilization
KW - leprosy
KW - Male
KW - Mali
KW - Microbial Sensitivity Tests
KW - Middle Aged
KW - Pseudomonas
KW - Pseudomonas Infections
KW - Retrospective Studies
KW - Skin Diseases, Bacterial
KW - Staphylococcal Skin Infections
KW - Staphylococcus aureus
AU - Tiendrebéogo A
AU - Coulibaly I
AU - Sarr A M
AU - Sow S O
AB - <p>To determine potential usefulness of antimicrobial agents and to guide their prescription in the treatment of leprosy plantar ulcers, we conducted an in vitro study about germs' nature and sensitivity to antibiotics. We took samples of plantar ulcers secretion from 107 patients at Marchoux Institute. 92.5% of those ulcers were infected. These samples revealed 145 strains of micro-organisms among those, Staphylococcus aureus (70 strains) and genus Pseudomonas (41 strains) were the most frequent. These bacteria were resistant to several antibiotics currently used at Marchoux Institute (tetracycline, penicillin, cotrimoxazol and erythromicin). Antibiotics, efficient at 80% on tested strains, were expensive for patients. They cannot be recommended for the treatment of local infections. These results outline that the main treatment in plantar ulcers is based upon antiseptic solutions and keeping feet at rest. Antibiotherapy in case of extension of local infection would be based on the results of a previous study of sensitivity.</p>
BT - Acta leprologica
C1 - http://www.ncbi.nlm.nih.gov/pubmed/10987046?dopt=Abstract
DA - 1999
IS - 4
J2 - Acta Leprol
LA - fre
N2 - <p>To determine potential usefulness of antimicrobial agents and to guide their prescription in the treatment of leprosy plantar ulcers, we conducted an in vitro study about germs' nature and sensitivity to antibiotics. We took samples of plantar ulcers secretion from 107 patients at Marchoux Institute. 92.5% of those ulcers were infected. These samples revealed 145 strains of micro-organisms among those, Staphylococcus aureus (70 strains) and genus Pseudomonas (41 strains) were the most frequent. These bacteria were resistant to several antibiotics currently used at Marchoux Institute (tetracycline, penicillin, cotrimoxazol and erythromicin). Antibiotics, efficient at 80% on tested strains, were expensive for patients. They cannot be recommended for the treatment of local infections. These results outline that the main treatment in plantar ulcers is based upon antiseptic solutions and keeping feet at rest. Antibiotherapy in case of extension of local infection would be based on the results of a previous study of sensitivity.</p>
PY - 1999
SP - 153
EP - 9
T2 - Acta leprologica
TI - [Nature and sensitivity of bacteria superinfecting plantar ulcers caused by leprosy at the Marchoux Institute, Bamako, Mali].
VL - 11
SN - 0001-5938
ER -