Two antigens were tested and compared in relation to the 48-h Fernandez reaction. They were obtained from standard human and from standard armadillo lepromin. All the tests were negative in patients with lepromatous leprosy and highly positive in those with tuberculoid leprosy and in lepromin-positive contacts. There was total agreement in all tests done with the two types of antigen. The antigenic component has the following basic properties: it precipitates with 80% saturated ammonium sulfate; it is not destroyed by autoclaving or by treatment with 0.4% phenol; it is non-dialysable; and it is destroyed by treatment with trypsin.
BT - Bulletin of the World Health Organization C1 - http://www.ncbi.nlm.nih.gov/pubmed/1083306?dopt=Abstract DA - 1975 IS - 2 J2 - Bull. World Health Organ. LA - eng N2 -Two antigens were tested and compared in relation to the 48-h Fernandez reaction. They were obtained from standard human and from standard armadillo lepromin. All the tests were negative in patients with lepromatous leprosy and highly positive in those with tuberculoid leprosy and in lepromin-positive contacts. There was total agreement in all tests done with the two types of antigen. The antigenic component has the following basic properties: it precipitates with 80% saturated ammonium sulfate; it is not destroyed by autoclaving or by treatment with 0.4% phenol; it is non-dialysable; and it is destroyed by treatment with trypsin.
PY - 1975 SP - 187 EP - 91 T2 - Bulletin of the World Health Organization TI - Specificity of the 48-hour reaction to Mitsuda antigen. Use of a soluble antigen from human and armadillo lepromin. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366352/pdf/bullwho00464-0063.pdf VL - 52 SN - 0042-9686 ER -