Human mycobacterial infections are characterized by a spectrum of clinical and immunological manifestations. Specific human leukocyte antigen (HLA) factors are associated with the subtypes of leprosy that develop and the course of tuberculosis after infection. The identification of protective mycobacterial antigens presented by a broad variety of HLA molecules will have important implications for the design of vaccines.
BT - Trends in microbiology C1 - http://www.ncbi.nlm.nih.gov/pubmed/9587192?dopt=Abstract DA - 1998 Apr DO - 10.1016/s0966-842x(98)01240-2 IS - 4 J2 - Trends Microbiol. LA - eng N2 -Human mycobacterial infections are characterized by a spectrum of clinical and immunological manifestations. Specific human leukocyte antigen (HLA) factors are associated with the subtypes of leprosy that develop and the course of tuberculosis after infection. The identification of protective mycobacterial antigens presented by a broad variety of HLA molecules will have important implications for the design of vaccines.
PY - 1998 SP - 148 EP - 54 T2 - Trends in microbiology TI - Human leukocyte antigens in tuberculosis and leprosy. VL - 6 SN - 0966-842X ER -