TY - JOUR KW - Clofazimine KW - Dapsone KW - Drug Resistance, Microbial KW - Drug Resistance, Multiple KW - Humans KW - Leprostatic Agents KW - leprosy KW - Microbial Sensitivity Tests KW - Mycobacterium leprae KW - Rifampin AU - Gupta U D AU - Katoch V M AB -

Some recent studies indicate that the problem of drug resistance in leprosy is very much there but the exact picture is not clear. In the emerging scenario with increasing number of new cases with low bacterial load, the conventional in-vivo and most of current in-vitro methods for determination of drug resistance may not help. It is pointed out that newer molecular approaches may be more useful and that it will be important to undertake studies to develop such tools.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/10804973?dopt=Abstract CN - Infolep Library - available DA - 1999 Oct-Dec IS - 4 J2 - Indian J Lepr LA - eng N2 -

Some recent studies indicate that the problem of drug resistance in leprosy is very much there but the exact picture is not clear. In the emerging scenario with increasing number of new cases with low bacterial load, the conventional in-vivo and most of current in-vitro methods for determination of drug resistance may not help. It is pointed out that newer molecular approaches may be more useful and that it will be important to undertake studies to develop such tools.

PY - 1999 SP - 451 EP - 63 T2 - Indian journal of leprosy TI - Drug resistance in leprosy: lessons from past and future perspective. VL - 71 SN - 0254-9395 ER -