TY - JOUR KW - Age Factors KW - BCG Vaccine KW - Case-Control Studies KW - Child KW - Child, Preschool KW - Female KW - Humans KW - Infant KW - Infant, Newborn KW - Male KW - Socioeconomic Factors KW - Tuberculosis, Meningeal AU - Zodpey S P AU - Maldhure B R AU - Shrikhande S N AU - Tiwari R R AB -
A hospital-based pair-matched case-control study was carried out at Government Medical College Hospital, Nagpur to estimate the effectiveness of bacillus of Calmette-Guerin (BCG) vaccination against tuberculous meningitis. The study included 92 cases of tuberculous meningitis in the age group of 0-12 years and equal number of controls, matched for age, sex and socio-economic status. The protective effectiveness and prevented fraction were higher for the subjects in the age group of 0-6 years, males and subjects from upper strata of socio-economic class. The overall vaccine effectiveness and prevented fraction were estimated to be 86.54% (70.38-93.88%) and 65.54% (39.22-80.64%) respectively. Results of this study thus indicated that BCG vaccination was highly effective against tuberculous meningitis and played significant role in its prevention, in this population.
BT - Journal of the Indian Medical Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/9019079?dopt=Abstract DA - 1996 Sep IS - 9 J2 - J Indian Med Assoc LA - eng N2 -A hospital-based pair-matched case-control study was carried out at Government Medical College Hospital, Nagpur to estimate the effectiveness of bacillus of Calmette-Guerin (BCG) vaccination against tuberculous meningitis. The study included 92 cases of tuberculous meningitis in the age group of 0-12 years and equal number of controls, matched for age, sex and socio-economic status. The protective effectiveness and prevented fraction were higher for the subjects in the age group of 0-6 years, males and subjects from upper strata of socio-economic class. The overall vaccine effectiveness and prevented fraction were estimated to be 86.54% (70.38-93.88%) and 65.54% (39.22-80.64%) respectively. Results of this study thus indicated that BCG vaccination was highly effective against tuberculous meningitis and played significant role in its prevention, in this population.
PY - 1996 SP - 338 EP - 40 T2 - Journal of the Indian Medical Association TI - Effectiveness of bacillus of Calmette-Guerin (BCG) vaccination against tuberculous meningitis: a case-control study. VL - 94 SN - 0019-5847 ER -