TY - JOUR KW - Animals KW - Antibodies, Bacterial KW - Antifungal Agents KW - Antigens, Bacterial KW - Antimalarials KW - Cell Membrane KW - Chloroquine KW - Enzyme-Linked Immunosorbent Assay KW - Interferon-gamma KW - Kinetics KW - leprosy KW - Mice KW - Monensin KW - Mycobacterium leprae KW - Recombinant Proteins KW - Schwann Cells AU - Birdi T J AU - D'Souza S AU - Antia N H AB -

Mycobacterial antigens were detected in a cell surface ELISA on murine dissociated Schwann cells infected with Mycobacterium leprae. The time kinetics of expression and its refractoriness to modulation with monensin suggests that the antigens are likely to be integrated into the membrane during bacterial entry. This may be partially responsible for the defective Schwann cell functions leading to subsequent peripheral nerve damage.

BT - Microbial pathogenesis C1 - http://www.ncbi.nlm.nih.gov/pubmed/9075220?dopt=Abstract DA - 1997 Mar IS - 3 J2 - Microb. Pathog. LA - eng N2 -

Mycobacterial antigens were detected in a cell surface ELISA on murine dissociated Schwann cells infected with Mycobacterium leprae. The time kinetics of expression and its refractoriness to modulation with monensin suggests that the antigens are likely to be integrated into the membrane during bacterial entry. This may be partially responsible for the defective Schwann cell functions leading to subsequent peripheral nerve damage.

PY - 1997 SP - 181 EP - 5 T2 - Microbial pathogenesis TI - Expression of mycobacterial antigens on murine dissociated Schwann cells infected with Mycobacterium leprae. VL - 22 SN - 0882-4010 ER -