TY - JOUR KW - AIDS-Related Opportunistic Infections KW - Antibody Formation KW - Genetic Markers KW - Humans KW - leprosy KW - Mycobacterium leprae KW - World Health Organization AU - Kociecka W AB -

Contemporary problems have been presented, related to pathogenesis, clinical pathology and epidemiology of leprosy. It has been stressed that intensity of cell mediated immune response in the patient determines not only resistance or susceptibility to infection with Mycobacterium leprae but also defines traits of clinical pathology in leprosy, thus providing the basis for modern clinical classification. Present aims and investigative methods in lepra epidemiology have been shown. Current data have been provided on spread of leprosy in various parts of the world, mainly those remaining under monitoring by the World Health Organization. The data point to significant decrease in registered leprosy cases in the regions beginning from 1986 and, in particular, in years 1990-1994. The decrease has resulted from adequate verification of the disease stage in the patients and from applying the recommended multidrug therapy. The needs and perspectives of actions aiming at combatting leprosy have been described, aiming at eradication of leprosy as the international health problem till the year 2000. It has been stressed that at present, leprosy is no longer a hopeless disease and that it can be cured when sufficiently early diagnosed and properly treated.

BT - Wiadomosci parazytologiczne C1 - http://www.ncbi.nlm.nih.gov/pubmed/8834501?dopt=Abstract DA - 1995 IS - 4 J2 - Wiad Parazytol LA - pol N2 -

Contemporary problems have been presented, related to pathogenesis, clinical pathology and epidemiology of leprosy. It has been stressed that intensity of cell mediated immune response in the patient determines not only resistance or susceptibility to infection with Mycobacterium leprae but also defines traits of clinical pathology in leprosy, thus providing the basis for modern clinical classification. Present aims and investigative methods in lepra epidemiology have been shown. Current data have been provided on spread of leprosy in various parts of the world, mainly those remaining under monitoring by the World Health Organization. The data point to significant decrease in registered leprosy cases in the regions beginning from 1986 and, in particular, in years 1990-1994. The decrease has resulted from adequate verification of the disease stage in the patients and from applying the recommended multidrug therapy. The needs and perspectives of actions aiming at combatting leprosy have been described, aiming at eradication of leprosy as the international health problem till the year 2000. It has been stressed that at present, leprosy is no longer a hopeless disease and that it can be cured when sufficiently early diagnosed and properly treated.

PY - 1995 SP - 373 EP - 90 T2 - Wiadomosci parazytologiczne TI - [Contemporary problems in the epidemiology and clinical pathology of leprosy]. VL - 41 SN - 0043-5163 ER -