TY - JOUR KW - Antigens, Bacterial KW - Humans KW - leprosy KW - Mycobacterium leprae KW - Serologic Tests KW - T-Lymphocytes AU - Thole J E AU - Wieles B AU - Clark-Curtiss J E AU - Ottenhoff T H AU - Rinke de Wit T F AB -
A major focus of leprosy research in the last 10 years has been the identification and characterization of antigens of Mycobacterium leprae that interact with antibodies and T cells of the host's immune response. Through the combined efforts of many different laboratories, a substantial number of protein antigens have been identified and characterized. In this MicroReview we present an updated list of M. leprae protein antigens, and, with emphasis on recent developments, summarize what is known regarding their functional and immunological features.
BT - Molecular microbiology C1 - http://www.ncbi.nlm.nih.gov/pubmed/8825083?dopt=Abstract DA - 1995 Dec DO - 10.1111/j.1365-2958.1995.18050791.x IS - 5 J2 - Mol. Microbiol. LA - eng N2 -A major focus of leprosy research in the last 10 years has been the identification and characterization of antigens of Mycobacterium leprae that interact with antibodies and T cells of the host's immune response. Through the combined efforts of many different laboratories, a substantial number of protein antigens have been identified and characterized. In this MicroReview we present an updated list of M. leprae protein antigens, and, with emphasis on recent developments, summarize what is known regarding their functional and immunological features.
PY - 1995 SP - 791 EP - 800 T2 - Molecular microbiology TI - Immunological and functional characterization of Mycobacterium leprae protein antigens: an overview. VL - 18 SN - 0950-382X ER -