TY - JOUR
KW - Biopsy
KW - Coloring Agents
KW - Double-Blind Method
KW - Granuloma
KW - Humans
KW - leprosy
KW - Leprosy, Borderline
KW - Leprosy, lepromatous
KW - Lymphocytes
KW - Prospective Studies
KW - Skin
KW - Skin Diseases
AU - Singh N
AU - Bhatia A
AU - Gupta K
AU - Ramam M
AB - <p><b>OBJECTIVE: </b>To evaluate the possible role of cytology in classifying leprosy lesions on the Ridley-Jopling scale.</p><p><b>STUDY DESIGN: </b>A double-blind, prospective study comparing cytologic assessment of 30 clinically diagnosed cases of leprosy with their histopathology. May-Grünwald-Giemsa and Ziehl-Neelsen stain were done on slit skin smears and fine needle aspiration material.</p><p><b>RESULTS: </b>Cytologic subclassification was possible in 23 cases as tuberculoid leprosy (11), midborderline (3), borderline lepromatous (5) and lepromatous leprosy (4). These correlated with histologic subtypes.</p><p><b>CONCLUSION: </b>May-Grünwald-Giemsa complements Ziehl-Neelsen stain, yielding information almost comparable to that from histologic examination of skin biopsies.</p>
BT - Acta cytologica
C1 - http://www.ncbi.nlm.nih.gov/pubmed/8693892?dopt=Abstract
DA - 1996 Jul-Aug
DO - 10.1159/000333945
IS - 4
J2 - Acta Cytol.
LA - eng
N2 - <p><b>OBJECTIVE: </b>To evaluate the possible role of cytology in classifying leprosy lesions on the Ridley-Jopling scale.</p><p><b>STUDY DESIGN: </b>A double-blind, prospective study comparing cytologic assessment of 30 clinically diagnosed cases of leprosy with their histopathology. May-Grünwald-Giemsa and Ziehl-Neelsen stain were done on slit skin smears and fine needle aspiration material.</p><p><b>RESULTS: </b>Cytologic subclassification was possible in 23 cases as tuberculoid leprosy (11), midborderline (3), borderline lepromatous (5) and lepromatous leprosy (4). These correlated with histologic subtypes.</p><p><b>CONCLUSION: </b>May-Grünwald-Giemsa complements Ziehl-Neelsen stain, yielding information almost comparable to that from histologic examination of skin biopsies.</p>
PY - 1996
SP - 719
EP - 23
T2 - Acta cytologica
TI - Cytomorphology of leprosy across the Ridley-Jopling spectrum.
VL - 40
SN - 0001-5547
ER -