TY - JOUR KW - Adult KW - Arthritis KW - C-Reactive Protein KW - Humans KW - Immunoglobulin A KW - Immunoglobulin G KW - Immunoglobulin M KW - leprosy KW - Rheumatoid Factor AU - Pal S AU - Singh S B AU - Bhattacharya S K AB -

Twelve patients of leprosy with arthritis and 161 patients without arthritis were studied for immunological parameters like immunoglobulins (IgG, IgM, IgA), C-reactive proteins and rheumatoid factor. There was increase in the levels of IgG, IgA value in leprosy patients with and without arthritis compared to healthy control. IgM level was decreased in both the groups compared to control, but significant decrease was observed (p < .01) in patients with arthritis. C-reactive protein was significantly positive in leprosy with arthritis group (p < .01) and positive in 12 cases of leprosy without arthritis group compared to negative control group. Rheumatoid factor was present in leprosy with arthritis (16.6%) compared to both the control group and leprosy without arthritis group. This study concluded the presence of arthritis in leprosy patients as a definite entity which showed changes in immunological parameters.

BT - Journal of the Indian Medical Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/8576590?dopt=Abstract DA - 1995 Jul IS - 7 J2 - J Indian Med Assoc LA - eng N2 -

Twelve patients of leprosy with arthritis and 161 patients without arthritis were studied for immunological parameters like immunoglobulins (IgG, IgM, IgA), C-reactive proteins and rheumatoid factor. There was increase in the levels of IgG, IgA value in leprosy patients with and without arthritis compared to healthy control. IgM level was decreased in both the groups compared to control, but significant decrease was observed (p < .01) in patients with arthritis. C-reactive protein was significantly positive in leprosy with arthritis group (p < .01) and positive in 12 cases of leprosy without arthritis group compared to negative control group. Rheumatoid factor was present in leprosy with arthritis (16.6%) compared to both the control group and leprosy without arthritis group. This study concluded the presence of arthritis in leprosy patients as a definite entity which showed changes in immunological parameters.

PY - 1995 SP - 266 EP - 7 T2 - Journal of the Indian Medical Association TI - Immunological parameters in leprosy patients with and without arthritis. VL - 93 SN - 0019-5847 ER -