TY - JOUR
KW - B-Lymphocytes
KW - Epithelioid Cells
KW - Giant Cells, Langhans
KW - Humans
KW - leprosy
KW - Mycobacterium leprae
KW - Periapical Granuloma
KW - T-Lymphocytes
AU - Tani-Ishii N
AU - Osada T
AU - WATANABE Y
AU - Umemoto T
AB - <p>Histological analysis of human leprosy periapical granulomas was conducted to study the histological responses to Mycobacterium leprae. Many Langhans-type giant cells and epithelioid cell tubercles were observed, although M. leprae were not detected in leprosy periapical granulomas. Although numerous T- and B-cells were infiltrated in leprosy periapical granuloma, the T-/B-cell ratio of leprosy is not changed to that of periapical granulomas isolated from normal patients. These findings suggested that human leprosy periapical granulomas develop as a result of immunological responses to M. leprae.</p>
BT - Journal of endodontics
C1 - http://www.ncbi.nlm.nih.gov/pubmed/8618092?dopt=Abstract
DA - 1996 Mar
DO - 10.1016/S0099-2399(96)80287-1
IS - 3
J2 - J Endod
LA - eng
N2 - <p>Histological analysis of human leprosy periapical granulomas was conducted to study the histological responses to Mycobacterium leprae. Many Langhans-type giant cells and epithelioid cell tubercles were observed, although M. leprae were not detected in leprosy periapical granulomas. Although numerous T- and B-cells were infiltrated in leprosy periapical granuloma, the T-/B-cell ratio of leprosy is not changed to that of periapical granulomas isolated from normal patients. These findings suggested that human leprosy periapical granulomas develop as a result of immunological responses to M. leprae.</p>
PY - 1996
SP - 120
EP - 2
T2 - Journal of endodontics
TI - Histological findings of human leprosy periapical granulomas.
VL - 22
SN - 0099-2399
ER -