TY - JOUR
KW - Animals
KW - Armadillos
KW - Humans
KW - Lepromin
KW - leprosy
KW - Skin Tests
KW - United States
AU - Krotoski W A
AU - Mroczkowski T F
AU - Rea T H
AU - Almodóvar P I
AU - Clements B C
AU - Neimes R E
AU - Kahkonen M K
AU - Job C K
AU - Hastings R C
AB - <p>Hansen's disease, or leprosy, although a relatively uncommon disease in the United States, continues to be important because of its implications--physical, psychological, and social--for the patient. Prognosis and treatment of the disease are based largely on clinical classification, which ranges from the multibacillary "lepromatous" to the paucibacillary "tuberculoid" forms, depending on the patient's specific immune capabilities. Traditionally, skin testing with lepromins--suspensions of the etiologic agent of Hansen's disease, Mycobacterium leprae--have been used as adjuncts to clinical parameters for classification in endemic areas. However, these have not been systematically studied in the United States. This report describes the results obtained from skin testing 38 volunteers (22 patients and 16 uninfected persons) with standard lepromin preparations. These results support the adjunctive value of lepromins for clinically classifying Hansen's disease in our "hypoendemic" population.</p>
BT - The American journal of the medical sciences
C1 - http://www.ncbi.nlm.nih.gov/pubmed/8416677?dopt=Abstract
DA - 1993 Jan
DO - 10.1097/00000441-199301000-00004
IS - 1
J2 - Am. J. Med. Sci.
LA - eng
N2 - <p>Hansen's disease, or leprosy, although a relatively uncommon disease in the United States, continues to be important because of its implications--physical, psychological, and social--for the patient. Prognosis and treatment of the disease are based largely on clinical classification, which ranges from the multibacillary "lepromatous" to the paucibacillary "tuberculoid" forms, depending on the patient's specific immune capabilities. Traditionally, skin testing with lepromins--suspensions of the etiologic agent of Hansen's disease, Mycobacterium leprae--have been used as adjuncts to clinical parameters for classification in endemic areas. However, these have not been systematically studied in the United States. This report describes the results obtained from skin testing 38 volunteers (22 patients and 16 uninfected persons) with standard lepromin preparations. These results support the adjunctive value of lepromins for clinically classifying Hansen's disease in our "hypoendemic" population.</p>
PY - 1993
SP - 18
EP - 24
T2 - The American journal of the medical sciences
TI - Lepromin skin testing in the classification of Hansen's disease in the United States.
VL - 305
SN - 0002-9629
ER -