TY - JOUR KW - Animals KW - Antibody-Dependent Cell Cytotoxicity KW - Antigen-Antibody Complex KW - Colony Count, Microbial KW - Immune Tolerance KW - Immunity, Cellular KW - In Vitro Techniques KW - Killer Cells, Natural KW - leprosy KW - Mice KW - Mycobacterium leprae KW - Time Factors AU - Vaishnavi C AU - Ganguly N K AU - Kaur S AU - Kumar B AB -
Antibody-dependent cellular cytotoxicity (ADCC) was assessed in mice infected experimentally with Mycobacterium leprae and injected simultaneously with in vitro-formed immune complexes (IC). Significant decrease in the ADCC function was observed in animals given IC at zero day (0dIC) and 3 months (3mIC) post inoculation with M. leprae, when ADCC activity was assessed at 3, 6 and 9 months period. From the data obtained we believe that ADCC is suppressed by IC formed in vitro.
BT - Microbiology and immunology C1 - http://www.ncbi.nlm.nih.gov/pubmed/8474357?dopt=Abstract DA - 1993 DO - 10.1111/j.1348-0421.1993.tb03178.x IS - 1 J2 - Microbiol. Immunol. LA - eng N2 -Antibody-dependent cellular cytotoxicity (ADCC) was assessed in mice infected experimentally with Mycobacterium leprae and injected simultaneously with in vitro-formed immune complexes (IC). Significant decrease in the ADCC function was observed in animals given IC at zero day (0dIC) and 3 months (3mIC) post inoculation with M. leprae, when ADCC activity was assessed at 3, 6 and 9 months period. From the data obtained we believe that ADCC is suppressed by IC formed in vitro.
PY - 1993 SP - 49 EP - 53 T2 - Microbiology and immunology TI - Suppression of ADCC by immune complexes formed in vitro in Mycobacterium leprae-infected mice. VL - 37 SN - 0385-5600 ER -