TY - JOUR KW - Adolescent KW - Adult KW - BCG Vaccine KW - Case-Control Studies KW - Female KW - Humans KW - leprosy KW - Malawi KW - Male KW - Odds Ratio AU - Baker D M AU - Nguyen-Van-Tam J S AU - Smith S J AB -
This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malaŵi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.
BT - Epidemiology and infection C1 - http://www.ncbi.nlm.nih.gov/pubmed/8348929?dopt=Abstract CN - BAKER1993 DA - 1993 Aug DO - 10.1017/s0950268800056636 IS - 1 J2 - Epidemiol. Infect. LA - eng N2 -This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malaŵi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.
PY - 1993 SP - 21 EP - 5 T2 - Epidemiology and infection TI - Protective efficacy of BCG vaccine against leprosy in southern Malaŵi. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271193/pdf/epidinfect00040-0030.pdf VL - 111 SN - 0950-2688 ER -