TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Albuminuria KW - Beta 2-Microglobulin KW - Biomarkers KW - Child KW - Creatinine KW - Female KW - Hematuria KW - Humans KW - Kidney Diseases KW - leprosy KW - Male KW - Middle Aged AU - Kirsztajn G M AU - Nishida S K AU - SILVA M S AU - Ajzen H AU - Pereira A B AB -
We have evaluated laboratory and clinical manifestations of renal disease in 96 patients with leprosy, looking for a sensitive and early marker for detection and possibly follow-up of nephropathy in these patients. Microscopic hematuria was observed in 21.9% of the cases (with dysmorphic erythrocytes in 71.4% of them). Abnormal microalbuminuria and urinary beta 2-microglobulin were found in 15.8 and 19.8% of the cases, respectively. We have observed a high frequency of hematuria, abnormal microalbuminuria and elevation of urinary beta 2-microglobulin in these patients still with normal serum creatinine.
BT - Nephron C1 - http://www.ncbi.nlm.nih.gov/pubmed/8289988?dopt=Abstract DA - 1993 DO - 10.1159/000187517 IS - 3 J2 - Nephron LA - eng N2 -We have evaluated laboratory and clinical manifestations of renal disease in 96 patients with leprosy, looking for a sensitive and early marker for detection and possibly follow-up of nephropathy in these patients. Microscopic hematuria was observed in 21.9% of the cases (with dysmorphic erythrocytes in 71.4% of them). Abnormal microalbuminuria and urinary beta 2-microglobulin were found in 15.8 and 19.8% of the cases, respectively. We have observed a high frequency of hematuria, abnormal microalbuminuria and elevation of urinary beta 2-microglobulin in these patients still with normal serum creatinine.
PY - 1993 SP - 381 EP - 4 T2 - Nephron TI - Renal abnormalities in leprosy. VL - 65 SN - 1660-8151 ER -