A total of 30 leprosy patients (controls n = 16; topical phenytoin n = 14) with trophic ulcers on the feet were investigated to ascertain the efficacy of topical phenytoin powder in the healing of ulcers. The ulcers in the two groups were matched for initial size. Healing patterns were assessed by determining changes in depth and planar (surface) dimensions at weekly intervals over a three week study period. Results indicate that while immobilization of the ulcer site is effective in promoting ulcer healing, additional use of topical phenytoin accelerates the healing process. There may however be non-responders to topical phenytoin.
BT - The Southeast Asian journal of tropical medicine and public health C1 - http://www.ncbi.nlm.nih.gov/pubmed/8266239?dopt=Abstract DA - 1993 Jun IS - 2 J2 - Southeast Asian J. Trop. Med. Public Health LA - eng N2 -A total of 30 leprosy patients (controls n = 16; topical phenytoin n = 14) with trophic ulcers on the feet were investigated to ascertain the efficacy of topical phenytoin powder in the healing of ulcers. The ulcers in the two groups were matched for initial size. Healing patterns were assessed by determining changes in depth and planar (surface) dimensions at weekly intervals over a three week study period. Results indicate that while immobilization of the ulcer site is effective in promoting ulcer healing, additional use of topical phenytoin accelerates the healing process. There may however be non-responders to topical phenytoin.
PY - 1993 SP - 340 EP - 2 T2 - The Southeast Asian journal of tropical medicine and public health TI - The use of topical phenytoin as an adjunct to immobilization in the treatment of trophic leprosy ulcers. VL - 24 SN - 0125-1562 ER -