TY - JOUR
KW - Adolescent
KW - Adult
KW - Age Distribution
KW - BCG Vaccine
KW - Case-Control Studies
KW - Child
KW - Child, Preschool
KW - Confidence Intervals
KW - Female
KW - Humans
KW - Incidence
KW - Kenya
KW - leprosy
KW - Male
KW - Middle Aged
KW - Odds Ratio
KW - Regression Analysis
KW - Risk Factors
KW - Sex Distribution
KW - Tuberculosis
AU - Orege P A
AU - Fine PE
AU - Lucas S B
AU - Obura M
AU - Okelo C
AU - Okuku P
AB - <p>A case-control study was carried out in western Kenya to measure the protection imparted by BCG against leprosy and tuberculosis. The study involved 69 newly diagnosed leprosy cases, 238 age-, sex- and neighborhood-matched controls, and 144 newly diagnosed, sputum-smear-positive tuberculosis cases along with 432 age-, sex- and neighborhood-matched controls. Information on BCG vaccination history was inferred from scars. Using matched analysis, the protection imparted by BCG against leprosy was estimated to be 81% [95% confidence interval (CI) = 67-90] with no apparent difference in protection against paucibacillary [vaccine efficacy (VE) = 83%, 95% CI = 58-92] and multibacillary leprosy (VE = 76%; 95% CI = 30-91). The effectiveness against tuberculosis was appreciably lower (VE = 22%) and was not statistically significant (95% CI = -20-51).</p>

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
C1 - <p>http://www.ncbi.nlm.nih.gov/pubmed/8151184?dopt=Abstract</p>

DA - 1993 Dec
IS - 4
J2 - Int. J. Lepr. Other Mycobact. Dis.
LA - eng
N2 - <p>A case-control study was carried out in western Kenya to measure the protection imparted by BCG against leprosy and tuberculosis. The study involved 69 newly diagnosed leprosy cases, 238 age-, sex- and neighborhood-matched controls, and 144 newly diagnosed, sputum-smear-positive tuberculosis cases along with 432 age-, sex- and neighborhood-matched controls. Information on BCG vaccination history was inferred from scars. Using matched analysis, the protection imparted by BCG against leprosy was estimated to be 81% [95% confidence interval (CI) = 67-90] with no apparent difference in protection against paucibacillary [vaccine efficacy (VE) = 83%, 95% CI = 58-92] and multibacillary leprosy (VE = 76%; 95% CI = 30-91). The effectiveness against tuberculosis was appreciably lower (VE = 22%) and was not statistically significant (95% CI = -20-51).</p>

PY - 1993
SP - 542
EP - 9
T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
TI - Case-control study of BCG vaccination as a risk factor for leprosy and tuberculosis in western Kenya.
UR - http://ila.ilsl.br/pdfs/v61n4a02.pdf
VL - 61
SN - 0148-916X
ER -