TY - JOUR KW - Adolescent KW - Adult KW - Antibodies, Bacterial KW - Antigen-Antibody Reactions KW - Contact Tracing KW - Evaluation Studies as Topic KW - Female KW - Humans KW - leprosy KW - Male KW - Middle Aged KW - Mycobacterium leprae AU - Singh N B AU - Bhatnagar S AU - Choudhary A AU - Gupta H P AU - Kaul S M AB -
A comparative evaluation of diversified antigens in ELISA has been made for detection of M. leprae antibodies in the sera of leprosy patients and their contacts. Out of the four antigens, namely M. leprae sonicate (ML), phenolic glycolipid I (PGL-1), M. habana sonicate (MH) and its arabinomannan (AM), the cross reactive antigens (MH,AM) have comparatively detected more number of leprosy cases. Homologous antigens (ML, PGL-1) have lower detection level. Use of MH and AM for detection of mycobacterial antibodies have been discussed and advocated for epidemiological studies of leprosy/tuberculosis.
BT - Indian journal of experimental biology C1 - http://www.ncbi.nlm.nih.gov/pubmed/7959924?dopt=Abstract DA - 1994 Jul IS - 7 J2 - Indian J. Exp. Biol. LA - eng N2 -A comparative evaluation of diversified antigens in ELISA has been made for detection of M. leprae antibodies in the sera of leprosy patients and their contacts. Out of the four antigens, namely M. leprae sonicate (ML), phenolic glycolipid I (PGL-1), M. habana sonicate (MH) and its arabinomannan (AM), the cross reactive antigens (MH,AM) have comparatively detected more number of leprosy cases. Homologous antigens (ML, PGL-1) have lower detection level. Use of MH and AM for detection of mycobacterial antibodies have been discussed and advocated for epidemiological studies of leprosy/tuberculosis.
PY - 1994 SP - 478 EP - 81 T2 - Indian journal of experimental biology TI - Evaluation of diversified antigens for detection of Mycobacterium leprae antibodies from leprosy patients and contacts. VL - 32 SN - 0019-5189 ER -