TY - JOUR KW - Acquired Immunodeficiency Syndrome KW - Adolescent KW - Adult KW - Aged KW - Asia KW - Caribbean Region KW - Ethiopia KW - Europe KW - Female KW - HTLV-I Infections KW - HTLV-II Infections KW - Humans KW - Latin America KW - leprosy KW - Male KW - Middle Aged KW - New York City KW - Prevalence KW - South America AU - Glaser J B AU - Levis W R AU - Gruber T AU - Cabrera A AU - Poiesz B J AB -

One-hundred seven consecutive patients attending a New York Hansen's disease clinic from November 1990 through June 1991 were tested for retroviruses. This cohort included 58 patients diagnosed with Hansen's disease after the onset of the AIDS epidemic, 54 of whom immigrated to the United States before diagnosis of Hansen's disease (median, 7 years). The overall rate (1.9%) of human T cell lymphotropic virus (HTLV) type I infection was low. Two (3.6%) of 55 Caribbean-born patients had polymerase chain reaction (PCR)-documented HTLV-I infection, but this incidence was not higher than expected in persons without Hansen's disease. No patient had PCR-documented evidence of either HTLV-II or human immunodeficiency virus (HIV) type 1 infection. The low rate of HIV-1 among those studied was likely related to an absence of classic HIV risk behavior because about half of the cohort could have incubated Mycobacterium leprae for a prolonged period while infected with HIV-1.

BT - The Journal of infectious diseases C1 - http://www.ncbi.nlm.nih.gov/pubmed/7930695?dopt=Abstract DA - 1994 Oct DO - 10.1093/infdis/170.4.1007 IS - 4 J2 - J. Infect. Dis. LA - eng N2 -

One-hundred seven consecutive patients attending a New York Hansen's disease clinic from November 1990 through June 1991 were tested for retroviruses. This cohort included 58 patients diagnosed with Hansen's disease after the onset of the AIDS epidemic, 54 of whom immigrated to the United States before diagnosis of Hansen's disease (median, 7 years). The overall rate (1.9%) of human T cell lymphotropic virus (HTLV) type I infection was low. Two (3.6%) of 55 Caribbean-born patients had polymerase chain reaction (PCR)-documented HTLV-I infection, but this incidence was not higher than expected in persons without Hansen's disease. No patient had PCR-documented evidence of either HTLV-II or human immunodeficiency virus (HIV) type 1 infection. The low rate of HIV-1 among those studied was likely related to an absence of classic HIV risk behavior because about half of the cohort could have incubated Mycobacterium leprae for a prolonged period while infected with HIV-1.

PY - 1994 SP - 1007 EP - 9 T2 - The Journal of infectious diseases TI - Prevalence of human T cell lymphotropic virus (HTLV) types I and II and human immunodeficiency virus type 1 infections among persons with Hansen's disease in New York City. VL - 170 SN - 0022-1899 ER -