TY - JOUR KW - Aged KW - Aged, 80 and over KW - Alzheimer Disease KW - Amyloid beta-Peptides KW - Asian Continental Ancestry Group KW - Brain KW - Humans KW - Japan KW - Leprostatic Agents KW - leprosy KW - Neurons KW - Tau Proteins AU - Koya G AU - Tabira T AB -
By the advance of chemotherapy and aging of the inpatients with leprosy (mean age: 75.7 years), geriatric disease are becoming major problems in Japanese National Leprosarium. Dementia is not diagnosed inpatient with leprosy. After autopsy Alzheimer fibrillary tangle and senile plaques in the brain of aged leprosy is not easy demonstrated by routine stains. However, these is easy demonstrable a different senile plaque with accretion to the Alzheimer fibrillary tangle, if it employed the specific immunohistochemical method on these brain. We employed both tau protein and the divided beta protein, and each of protein is able to divide dementia and non-dementia into aged groups in leprosy. Low prevalence in Japanese leprosy patients is demonstrable in dementia of what happened was accurate in alzheimer disease with subtype of senile plaque.
BT - Nihon Rai Gakkai zasshi C1 - http://www.ncbi.nlm.nih.gov/pubmed/7844063?dopt=Abstract DA - 1994 Jul IS - 2 J2 - Nihon Rai Gakkai Zasshi LA - jpn N2 -By the advance of chemotherapy and aging of the inpatients with leprosy (mean age: 75.7 years), geriatric disease are becoming major problems in Japanese National Leprosarium. Dementia is not diagnosed inpatient with leprosy. After autopsy Alzheimer fibrillary tangle and senile plaques in the brain of aged leprosy is not easy demonstrated by routine stains. However, these is easy demonstrable a different senile plaque with accretion to the Alzheimer fibrillary tangle, if it employed the specific immunohistochemical method on these brain. We employed both tau protein and the divided beta protein, and each of protein is able to divide dementia and non-dementia into aged groups in leprosy. Low prevalence in Japanese leprosy patients is demonstrable in dementia of what happened was accurate in alzheimer disease with subtype of senile plaque.
PY - 1994 SP - 51 EP - 4 T2 - Nihon Rai Gakkai zasshi TI - [Is a false image of the senile plaque in elderly Japanese with leprosy?--pathological findings on the immunohistology]. VL - 63 SN - 0386-3980 ER -