A case of ocular leprosy as the manifestation of persistent or relapsed Mycobacterium leprae infection approximately 20 years following treatment is reported. The clinical and pathological features of this case are described, and the molecular methods needed to arrive at the definitive diagnosis are examined. If blindness is to be averted, clinicians must have a high index of suspicion for the diagnosis of ocular leprosy when anterior segment changes are noted during ophthalmologic examination of a patient from an area in which M. leprae is endemic. The indolent nature of ocular leprosy may require lifelong surveillance and therapy to insure sight preservation.
BT - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America C1 - http://www.ncbi.nlm.nih.gov/pubmed/7795073?dopt=Abstract DA - 1995 Apr DO - 10.1093/clinids/20.4.776 IS - 4 J2 - Clin. Infect. Dis. LA - eng N2 -A case of ocular leprosy as the manifestation of persistent or relapsed Mycobacterium leprae infection approximately 20 years following treatment is reported. The clinical and pathological features of this case are described, and the molecular methods needed to arrive at the definitive diagnosis are examined. If blindness is to be averted, clinicians must have a high index of suspicion for the diagnosis of ocular leprosy when anterior segment changes are noted during ophthalmologic examination of a patient from an area in which M. leprae is endemic. The indolent nature of ocular leprosy may require lifelong surveillance and therapy to insure sight preservation.
PY - 1995 SP - 776 EP - 80 T2 - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America TI - Relapse of Mycobacterium leprae infection with ocular manifestations. VL - 20 SN - 1058-4838 ER -