TY - JOUR KW - Adult KW - Aged KW - Epitopes KW - HLA Antigens KW - Humans KW - Japan KW - leprosy KW - Lymphocytes KW - Middle Aged KW - Phenotype KW - Tuberculosis AU - Takata H AU - Sada M AU - Ozawa S AU - Sekiguchi S AB -
A total of 60 leprosy patients, 28 of lepromatous and 32 of tuberculoid form, and 70 active tuberculosis patients was compared with a control of 184 for 34 HLA specificities. The most interesting finding was an increased frequency (10.0%) for HLA-B8 (corrected P = 0.062, relative risk = 20.3) in the leprosy patients as compared with the control group, despite the fact that the frequency of HLA-B8 was extremely low in Japanese. Furthermore, all leprosy patients with B8 had leprous member(s) in their family.
BT - Tissue antigens C1 - http://www.ncbi.nlm.nih.gov/pubmed/75590?dopt=Abstract DA - 1978 Jan DO - 10.1111/j.1399-0039.1978.tb01225.x IS - 1 J2 - Tissue Antigens LA - eng N2 -A total of 60 leprosy patients, 28 of lepromatous and 32 of tuberculoid form, and 70 active tuberculosis patients was compared with a control of 184 for 34 HLA specificities. The most interesting finding was an increased frequency (10.0%) for HLA-B8 (corrected P = 0.062, relative risk = 20.3) in the leprosy patients as compared with the control group, despite the fact that the frequency of HLA-B8 was extremely low in Japanese. Furthermore, all leprosy patients with B8 had leprous member(s) in their family.
PY - 1978 SP - 61 EP - 4 T2 - Tissue antigens TI - HLA and mycobacterial infection: increased frequency of B8 in Japanese leprosy. VL - 11 SN - 0001-2815 ER -