Multibacillary (MB) leprosy patients are declared cured when they become bacteriologically negative and their lesions do not show any signs of clinical activity. Whether there is also a corresponding histological clearance of skin lesions is not known. The present study was carried out on the histopathology of the skin of 40 MB cases who were declared cured with multidrug (MDT). In 22 of them, small lepromatous granulomas were seen to persist, although acidfast bacilli were not found in them. The presence of these granulomas was not found to have any significant associated with the duration of the disease, length of treatment, or the period of cessation of therapy.
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 -http://www.ncbi.nlm.nih.gov/pubmed/7594925?dopt=Abstract
DA - 1995 Sep IS - 3 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -Multibacillary (MB) leprosy patients are declared cured when they become bacteriologically negative and their lesions do not show any signs of clinical activity. Whether there is also a corresponding histological clearance of skin lesions is not known. The present study was carried out on the histopathology of the skin of 40 MB cases who were declared cured with multidrug (MDT). In 22 of them, small lepromatous granulomas were seen to persist, although acidfast bacilli were not found in them. The presence of these granulomas was not found to have any significant associated with the duration of the disease, length of treatment, or the period of cessation of therapy.
PY - 1995 SP - 417 EP - 21 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Persistence of lepromatous granuloma in clinically cured cases of leprosy. UR - http://ila.ilsl.br/pdfs/v63n3a06.pdf VL - 63 SN - 0148-916X ER -