TY - JOUR
KW - Adult
KW - Clofazimine
KW - Dapsone
KW - Drug Interactions
KW - Drug Therapy, Combination
KW - Humans
KW - Isoniazid
KW - leprosy
KW - Male
KW - Middle Aged
KW - Rifampin
AU - Venkatesan K
AU - Bharadwaj V P
AU - Ramu G
AU - Desikan K V
AB - <p>Studies on the interactions of the drugs used in combination therapy of leprosy were attempted at this Institute. INH supplementation with clofazimine, therapy appeared to lower the skin levels of clofazimine, raising the plasma and urinary content of clofazimine. Concurrent administration of clofazimine with DDS does not appear to exert any influence on the excretion of DDS. The plasma DDS lowering effect of Rifampicin does not vary between fast and slow acetylators for DDS.</p>
BT - Leprosy in India
C1 - http://www.ncbi.nlm.nih.gov/pubmed/7453137?dopt=Abstract
CN - Infolep Library - available
DA - 1980 Apr
IS - 2
J2 - Lepr India
LA - eng
N2 - <p>Studies on the interactions of the drugs used in combination therapy of leprosy were attempted at this Institute. INH supplementation with clofazimine, therapy appeared to lower the skin levels of clofazimine, raising the plasma and urinary content of clofazimine. Concurrent administration of clofazimine with DDS does not appear to exert any influence on the excretion of DDS. The plasma DDS lowering effect of Rifampicin does not vary between fast and slow acetylators for DDS.</p>
PY - 1980
SP - 229
EP - 35
T2 - Leprosy in India
TI - Study on drug interactions.
VL - 52
SN - 0024-1024
ER -