TY - JOUR KW - Amyloid KW - Amyloidosis KW - Animals KW - Arthritis, Juvenile KW - Blood Sedimentation KW - Chronic Disease KW - Female KW - Humans KW - leprosy KW - Leukocyte Count KW - Male KW - Osteomyelitis KW - Rabbits KW - Serum Amyloid A Protein AU - Scheinberg M A AU - Benson M D AB -

Serum amyloid protein A (SAA) levels were evaluated by a sensitive radioimmunoassay technique in leprosy, juvenile rheumatoid arthritis and chronic osteomyelitis. SAA was elevated in all 3 groups of patients. The level in each of the patient groups did not reflect the presence of secondary amyloidosis. Our study suggests that serum SAA protein levels should not be considered a routine diagnostic test in patients with chronic inflammatory diseases prone to the development of amyloid disease.

BT - The Journal of rheumatology C1 - http://www.ncbi.nlm.nih.gov/pubmed/7441662?dopt=Abstract DA - 1980 Sep-Oct IS - 5 J2 - J. Rheumatol. LA - eng N2 -

Serum amyloid protein A (SAA) levels were evaluated by a sensitive radioimmunoassay technique in leprosy, juvenile rheumatoid arthritis and chronic osteomyelitis. SAA was elevated in all 3 groups of patients. The level in each of the patient groups did not reflect the presence of secondary amyloidosis. Our study suggests that serum SAA protein levels should not be considered a routine diagnostic test in patients with chronic inflammatory diseases prone to the development of amyloid disease.

PY - 1980 SP - 724 EP - 6 T2 - The Journal of rheumatology TI - SAA amyloid protein levels in amyloid-prone chronic inflammatory disorders. Lack of association with amyloid disease. VL - 7 SN - 0315-162X ER -