TY - JOUR
KW - Adult
KW - Angiography
KW - Brachial Artery
KW - Female
KW - Humans
KW - leprosy
KW - Male
KW - Neural Conduction
KW - Neuritis
KW - Spinal Nerves
KW - Sural Nerve
KW - Ulnar nerve
KW - Vascular Diseases
AU - Chopra J S
AU - Kaur S
AU - Murthy J M
AU - Kumar B
AU - Radhakrishnan K
AU - Suri S
AU - Sawhney B B
AB - <p>The arteriographic pattern of left hand vessels was studied in 20 patients in leprosy by percutaneous brachial arteriography. Arteriographic abnormalities noted consisted of occlusion, narrowing, tortuosity, dilatation, irregularity and incomplete filling of the lumen by contrast medium. Such abnormal findings were seen in all the arteriograms studied and more than one vessel involvement was noted in over 50 percent cases. This study clearly demonstrated that arterial involvement in leprosy was frequent. No correlation was found between motor weakness and vascular abnormalities. There was no difference in arterial lesions between the patients with and without trophic changes. There was also no correlation between the severity of vascular changes and decline in motor nerve conduction. Degree of histopathological abnormalities in the sural nerve biopsy from these patients showed no features of micro angiopathic neuropathy. It is concluded that the observed vascular abnormalities do not contribute significantly in the genesis of neurological deficit in leprosy.</p>
BT - Leprosy in India
C1 - http://www.ncbi.nlm.nih.gov/pubmed/7278150?dopt=Abstract
CN - Infolep Library - available
DA - 1981 Jul
IS - 3
J2 - Lepr India
LA - eng
N2 - <p>The arteriographic pattern of left hand vessels was studied in 20 patients in leprosy by percutaneous brachial arteriography. Arteriographic abnormalities noted consisted of occlusion, narrowing, tortuosity, dilatation, irregularity and incomplete filling of the lumen by contrast medium. Such abnormal findings were seen in all the arteriograms studied and more than one vessel involvement was noted in over 50 percent cases. This study clearly demonstrated that arterial involvement in leprosy was frequent. No correlation was found between motor weakness and vascular abnormalities. There was no difference in arterial lesions between the patients with and without trophic changes. There was also no correlation between the severity of vascular changes and decline in motor nerve conduction. Degree of histopathological abnormalities in the sural nerve biopsy from these patients showed no features of micro angiopathic neuropathy. It is concluded that the observed vascular abnormalities do not contribute significantly in the genesis of neurological deficit in leprosy.</p>
PY - 1981
SP - 443
EP - 53
T2 - Leprosy in India
TI - Vascular changes in leprosy and its role in the pathogenesis of leprous neuritis.
VL - 53
SN - 0024-1024
ER -