The effect of treatment with a single dose of Rifampicin (1500 mg) has been investigated in previously untreated lepromatous leprosy patients. A group of 14 cases were administered 1500 mg of Rifampicin in a single dose along with 100 mg Dapsone (DDS) daily. A control group received only 100 mg DDS daily. The patients were followed up for a period of 24 weeks. The clinical, bacteriological and results of mouse foot-pad inoculations do not indicate a significant advantage of the addition of a single dose of Rifampicin to the conventional therapy with DDA.
BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/7206633?dopt=Abstract CN - Infolep Library - available DA - 1980 Jul IS - 3 J2 - Lepr India LA - eng N2 -The effect of treatment with a single dose of Rifampicin (1500 mg) has been investigated in previously untreated lepromatous leprosy patients. A group of 14 cases were administered 1500 mg of Rifampicin in a single dose along with 100 mg Dapsone (DDS) daily. A control group received only 100 mg DDS daily. The patients were followed up for a period of 24 weeks. The clinical, bacteriological and results of mouse foot-pad inoculations do not indicate a significant advantage of the addition of a single dose of Rifampicin to the conventional therapy with DDA.
PY - 1980 SP - 359 EP - 65 T2 - Leprosy in India TI - Effect of single dose (1500 mg) rifampicin on infectivity of patients with lepromatous leprosy. VL - 52 SN - 0024-1024 ER -