TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Anemia, Hemolytic KW - Bilirubin KW - Child KW - Dapsone KW - Female KW - Hemolysis KW - Humans KW - leprosy KW - Male KW - Middle Aged KW - Osmotic Fragility KW - Reticulocytes AU - Menezes S AU - Rege V L AU - Sehgal V N AB -

Fifty one patients with leprosy from the Urban Leprosy Centre, attached to the Department of Dermatology and Venereology, Goa Medical College on treatment with Dapsone were studied from the point of view of development of haemolysis related to the drug. The findings are described and discussed. Anaemia developed in 60.7 percent of the patients during the course of treatment. It was mild and well compensated. The haemolytic effect of dapsone was related to the dose and duration of the treatment, being more manifested in doses above 50 mg daily.

BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/7218764?dopt=Abstract CN - Infolep Library - available DA - 1981 Jan IS - 1 J2 - Lepr India LA - eng N2 -

Fifty one patients with leprosy from the Urban Leprosy Centre, attached to the Department of Dermatology and Venereology, Goa Medical College on treatment with Dapsone were studied from the point of view of development of haemolysis related to the drug. The findings are described and discussed. Anaemia developed in 60.7 percent of the patients during the course of treatment. It was mild and well compensated. The haemolytic effect of dapsone was related to the dose and duration of the treatment, being more manifested in doses above 50 mg daily.

PY - 1981 SP - 63 EP - 9 T2 - Leprosy in India TI - Dapsone haemolysis in leprosy. A preliminary report. VL - 53 SN - 0024-1024 ER -