Corticosteroids are known to influence the hypersensitivity reaction in a number of diseases involving hypersensitivity of tissues and alter the antigen antibody reactions in vivo. Corticosteroids administered in thirty tuberculoid cases for a period of 3 weeks showed negative response in the lepromin positive cases uniformly thereby proving suppression of cell mediated immunity in tuberculoid cases under the influence of corticosteroids; hence polar concept of tuberculoid type may be under question with continuous and prolonged corticosteroid therapy under necessity.
BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/7176537?dopt=Abstract CN - Infolep Library - available DA - 1982 Jul IS - 3 J2 - Lepr India LA - eng N2 -Corticosteroids are known to influence the hypersensitivity reaction in a number of diseases involving hypersensitivity of tissues and alter the antigen antibody reactions in vivo. Corticosteroids administered in thirty tuberculoid cases for a period of 3 weeks showed negative response in the lepromin positive cases uniformly thereby proving suppression of cell mediated immunity in tuberculoid cases under the influence of corticosteroids; hence polar concept of tuberculoid type may be under question with continuous and prolonged corticosteroid therapy under necessity.
PY - 1982 SP - 489 EP - 98 T2 - Leprosy in India TI - Corticosteroids and lepromin sensitivity. VL - 54 SN - 0024-1024 ER -