Serum enzyme profile was studied in 74 patients with Tuberculoid leprosy and compared with that of 100 healthy controls. The enzymes studied were Aspartate and Alanine Transaminase, Isocitric dehydrogenase, Alkaline phosphatase Choline esterase and Creatine kinase. Both Transaminase and Alkaline phosphatase were in general within normal limits in Tuberculoid leprosy. Creatine kinase levels were found to be significantly elevated. In some of these cases raised levels of Serum Aspartate Transaminase was also noticed--evidence for skeletal muscle destruction. Mild increases in Isocitric dehydrogenase and a concomitant increase in Alanine Transaminase in some of the patients suggest a sub-clinical hepatic damage. A statistically significant decrease in Serum Choline esterase level was noticed in this study on Tuberculoid leprosy patients.
BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/7098444?dopt=Abstract CN - Infolep Library - available DA - 1982 Jan IS - 1 J2 - Lepr India LA - eng N2 -Serum enzyme profile was studied in 74 patients with Tuberculoid leprosy and compared with that of 100 healthy controls. The enzymes studied were Aspartate and Alanine Transaminase, Isocitric dehydrogenase, Alkaline phosphatase Choline esterase and Creatine kinase. Both Transaminase and Alkaline phosphatase were in general within normal limits in Tuberculoid leprosy. Creatine kinase levels were found to be significantly elevated. In some of these cases raised levels of Serum Aspartate Transaminase was also noticed--evidence for skeletal muscle destruction. Mild increases in Isocitric dehydrogenase and a concomitant increase in Alanine Transaminase in some of the patients suggest a sub-clinical hepatic damage. A statistically significant decrease in Serum Choline esterase level was noticed in this study on Tuberculoid leprosy patients.
PY - 1982 SP - 69 EP - 74 T2 - Leprosy in India TI - Serum enzyme profile in tuberculoid leprosy. VL - 54 SN - 0024-1024 ER -