TY - JOUR KW - Diagnosis, Differential KW - Fluorescent Antibody Technique KW - Humans KW - Lupus Erythematosus, Discoid KW - Lupus Erythematosus, Systemic KW - Skin KW - Skin Diseases AU - Wallach D AU - Pelbois G AU - Cottenot F AB -

The lupus band test is usually considered as a valuable aid for the diagnosis of lupus erythematous. Involved skin shows positive results in about 900 p. 100 of cases of discoid LE and systemic LE. However, the specificity of this test has been challenged by reports of positive immunofluorescent findings in other cutaneous diseases, like rosacea, in non-cutaneous diseases, and in healthy individuals. Discrepant data from the literature prompted us to report our own experience : direct immunofluorescent examination of skin biopsies was performed in 550 patients from a dermatologic department. Concerning diseased skin, a dermal-epidermal band was observed only in 18 cases of lupus erythematosus, in 4 cases of lepromatous leprosy, in one case of vasculitis, one case of prurigo, and one case of dermatomyositis. Concerning healthy skin, a band was seen only in 8 cases of systemic lupus erythematosus. These results confirm other reports establishing the specificity of the lupus band test.

BT - Annales de medecine interne C1 - http://www.ncbi.nlm.nih.gov/pubmed/7039457?dopt=Abstract DA - 1981 IS - 8 J2 - Ann Med Interne (Paris) LA - fre N2 -

The lupus band test is usually considered as a valuable aid for the diagnosis of lupus erythematous. Involved skin shows positive results in about 900 p. 100 of cases of discoid LE and systemic LE. However, the specificity of this test has been challenged by reports of positive immunofluorescent findings in other cutaneous diseases, like rosacea, in non-cutaneous diseases, and in healthy individuals. Discrepant data from the literature prompted us to report our own experience : direct immunofluorescent examination of skin biopsies was performed in 550 patients from a dermatologic department. Concerning diseased skin, a dermal-epidermal band was observed only in 18 cases of lupus erythematosus, in 4 cases of lepromatous leprosy, in one case of vasculitis, one case of prurigo, and one case of dermatomyositis. Concerning healthy skin, a band was seen only in 8 cases of systemic lupus erythematosus. These results confirm other reports establishing the specificity of the lupus band test.

PY - 1981 SP - 535 EP - 9 T2 - Annales de medecine interne TI - [The specificity of the lupus band test. Personal findings and literature data (author's transl)]. VL - 132 SN - 0003-410X ER -