TY - JOUR
KW - Antibodies, Bacterial
KW - Female
KW - Fetal Blood
KW - Humans
KW - Immunoglobulin A
KW - Immunoglobulin M
KW - leprosy
KW - Maternal-Fetal Exchange
KW - Mycobacterium leprae
KW - Pregnancy
KW - Radioimmunoassay
AU - Melsom R
AU - Harboe M
AU - Duncan M E
AU - Bergsvik H
AB - <p>A solid-phase radioimmunoassay was developed for demonstration and quantification of IgA and IgM anti-M. leprae antibodies. IgA and IgM anti-M. leprae antibodies were demonstrated in a lepromatous serum pool, in various amounts in individual patients with lepromatous leprosy, and in lower concentration in tuberculoid leprosy and non-leprosy controls. IgA and IgM anti-M. leprae antibodies were demonstrated in cord sera from babies of mothers with leprosy. The reliability of fetal IgA and IgM antibody synthesis as an indicator of intrauterine infection in leprosy is discussed.</p>
BT - Scandinavian journal of immunology
C1 - http://www.ncbi.nlm.nih.gov/pubmed/7038849?dopt=Abstract
CN - MELSOM 1981
DA - 1981 Oct
DO - 10.1111/j.1365-3083.1981.tb00574.x
IS - 4
J2 - Scand. J. Immunol.
LA - eng
N2 - <p>A solid-phase radioimmunoassay was developed for demonstration and quantification of IgA and IgM anti-M. leprae antibodies. IgA and IgM anti-M. leprae antibodies were demonstrated in a lepromatous serum pool, in various amounts in individual patients with lepromatous leprosy, and in lower concentration in tuberculoid leprosy and non-leprosy controls. IgA and IgM anti-M. leprae antibodies were demonstrated in cord sera from babies of mothers with leprosy. The reliability of fetal IgA and IgM antibody synthesis as an indicator of intrauterine infection in leprosy is discussed.</p>
PY - 1981
SP - 343
EP - 52
T2 - Scandinavian journal of immunology
TI - IgA and IgM antibodies against Mycobacterium leprae in cord sera and in patients with leprosy: an indicator of intrauterine infection in leprosy.
VL - 14
SN - 0300-9475
ER -