TY - JOUR KW - Adult KW - Blood Transfusion KW - Dinitrochlorobenzene KW - Erythema Nodosum KW - Female KW - Humans KW - Lepromin KW - leprosy KW - Male KW - Middle Aged KW - Mycobacterium leprae KW - Time Factors KW - Tuberculin Test AU - Saha K AU - Mittal M M AU - Maheswari H B AB -

Earlier studies of immunologic reconstitution therapy of active lepromatous leprosy patients by repeated infusions of viable allogeneic blood lymphocytes indicated a beneficial effect. In order to avoid cell separation and its associated risks, we attempted to transfer immunity passively into seven seriously ill lepromatous patients by repeated transfusions of fresh blood donated by healthy, but tuberculin and lepromin positive, subjects. The results showed clinical improvement in some cases with the elimination of Mycobacterium leprae, histological reversion and return of immunologic responsiveness.

BT - Transfusion C1 - http://www.ncbi.nlm.nih.gov/pubmed/7041343?dopt=Abstract DA - 1982 Mar-Apr DO - 10.1046/j.1537-2995.1982.22282177120.x IS - 2 J2 - Transfusion LA - eng N2 -

Earlier studies of immunologic reconstitution therapy of active lepromatous leprosy patients by repeated infusions of viable allogeneic blood lymphocytes indicated a beneficial effect. In order to avoid cell separation and its associated risks, we attempted to transfer immunity passively into seven seriously ill lepromatous patients by repeated transfusions of fresh blood donated by healthy, but tuberculin and lepromin positive, subjects. The results showed clinical improvement in some cases with the elimination of Mycobacterium leprae, histological reversion and return of immunologic responsiveness.

PY - 1982 SP - 134 EP - 7 T2 - Transfusion TI - Reversion of the downhill course of active lepromatous leprosy by repeated transfusions of fresh blood, donated by healthy but lepromin positive patients. VL - 22 SN - 0041-1132 ER -