TY - JOUR
KW - Cell Membrane
KW - Cell Wall
KW - Clofazimine
KW - Dapsone
KW - Humans
KW - leprosy
KW - Microscopy, Electron
KW - Mycobacterium leprae
KW - Organoids
KW - Ribosomes
KW - Rifampin
KW - Skin
AU - Silva M T
AU - Macedo P M
AU - Costa M H
AU - Gonçalves H
AU - Torgal J
AU - David H L
AB - <p>1. -- Mycobacterium leprae cells under a process of progressive disaggregation are present in the skin of both treated and untreated patients. 2. -- The ultrastructural alterations observed during the degenerative process seem to be qualitatively similar in treated and untreated patients. 3. -- The proportion of altered M. leprae cells increases during the treatment, mainly with rifampicin and rifampicin + clofazimine + diaminodiphenyl sulfone. 4. -- The cell wall of M. leprae is the last bacterial structure to disappear during the degenerative process.</p>
BT - Annales de microbiologie
C1 - http://www.ncbi.nlm.nih.gov/pubmed/7051933?dopt=Abstract
DA - 1982 Jul-Aug
IS - 1
J2 - Ann. Microbiol. (Paris)
LA - eng
N2 - <p>1. -- Mycobacterium leprae cells under a process of progressive disaggregation are present in the skin of both treated and untreated patients. 2. -- The ultrastructural alterations observed during the degenerative process seem to be qualitatively similar in treated and untreated patients. 3. -- The proportion of altered M. leprae cells increases during the treatment, mainly with rifampicin and rifampicin + clofazimine + diaminodiphenyl sulfone. 4. -- The cell wall of M. leprae is the last bacterial structure to disappear during the degenerative process.</p>
PY - 1982
SP - 75
EP - 92
T2 - Annales de microbiologie
TI - Ultrastructural alterations of mycobacterium leprae in skin biopsies of untreated and treated lepromatous patients.
VL - 133
SN - 0300-5410
ER -