The content of T and B lymphocytes in the peripheral blood of patients with polar types of leprosy and healthy adults was determined. The lepromatous (severe) form of leprosy was found to be accompanied by a sharp decrease in the percentage of T lymphocytes, while the percentage of B lymphocytes perceptibly increased. In patients with the tuberculoid type of leprosy only an insignificant decrease in the percentage of T lymphocytes was observed, while the level of B lymphocytes remained normal. These data indicate that in the severe form of leprosy cellular immunity is deeply suppressed, and the nonspecific stimulation of humoral immunity occurs.
BT - Zhurnal mikrobiologii, epidemiologii, i immunobiologii C1 - http://www.ncbi.nlm.nih.gov/pubmed/6966450?dopt=Abstract DA - 1980 Jan IS - 1 J2 - Zh. Mikrobiol. Epidemiol. Immunobiol. LA - rus N2 -The content of T and B lymphocytes in the peripheral blood of patients with polar types of leprosy and healthy adults was determined. The lepromatous (severe) form of leprosy was found to be accompanied by a sharp decrease in the percentage of T lymphocytes, while the percentage of B lymphocytes perceptibly increased. In patients with the tuberculoid type of leprosy only an insignificant decrease in the percentage of T lymphocytes was observed, while the level of B lymphocytes remained normal. These data indicate that in the severe form of leprosy cellular immunity is deeply suppressed, and the nonspecific stimulation of humoral immunity occurs.
PY - 1980 SP - 62 EP - 4 T2 - Zhurnal mikrobiologii, epidemiologii, i immunobiologii TI - [Content of T- and B-lymphocytes in the blood of patients with polar types of leprosy]. SN - 0372-9311 ER -