TY - JOUR KW - Adult KW - Dapsone KW - Erythema Nodosum KW - Female KW - Humans KW - Ischemia KW - leprosy KW - Lymphopenia KW - Male KW - Middle Aged KW - Necrosis KW - Retrospective Studies KW - Skin KW - Thalidomide AU - Rea T H AU - Levan N E AB -
The records of ten patients with Lucio's phenomenon showed clinical and histopathological changes similar to those described by others. Lucio's phenomenon is a syndrome distinct from erythema nodosum leprosum as indicated by an absence of fever, leukocytosis and tenderness, a failure to respond to thalidomide, and a restriction to patients with diffuse nonnodular lepromatous leprosy. Lymphopenia associated with splenomegaly in three patients and glomerulonephritis in one patient were unexpected findings of unknown relevance.
BT - Archives of dermatology C1 - http://www.ncbi.nlm.nih.gov/pubmed/686719?dopt=Abstract DA - 1978 Jul IS - 7 J2 - Arch Dermatol LA - eng N2 -The records of ten patients with Lucio's phenomenon showed clinical and histopathological changes similar to those described by others. Lucio's phenomenon is a syndrome distinct from erythema nodosum leprosum as indicated by an absence of fever, leukocytosis and tenderness, a failure to respond to thalidomide, and a restriction to patients with diffuse nonnodular lepromatous leprosy. Lymphopenia associated with splenomegaly in three patients and glomerulonephritis in one patient were unexpected findings of unknown relevance.
PY - 1978 SP - 1023 EP - 8 T2 - Archives of dermatology TI - Lucio's phenomenon and diffuse nonnodular lepromatous leprosy. VL - 114 SN - 0003-987X ER -