TY - JOUR KW - Adolescent KW - Adult KW - Child KW - Dapsone KW - Drug Resistance, Microbial KW - Female KW - Humans KW - leprosy KW - Male KW - Mycobacterium leprae KW - Rifampin AU - Janssens L AB -

Two patients are presented with a primary resistant BT leprosy. Diagnosis was made on a clinical base: luck of improvement under supervised sulfone treatment and quick regression of the lesions under a short course of rifampicine (8 weekly doses). The two children lived together with their lepromatous mothers who are suspected of DDS resistance. Where secondary DDS resistance is found only in multibacillary leprosy, primary resistance shows up in all clinical forms of leprosy.

BT - Acta leprologica C1 - http://www.ncbi.nlm.nih.gov/pubmed/6815986?dopt=Abstract DA - 1982 Jan-Jun IS - 86-87 J2 - Acta Leprol LA - fre N2 -

Two patients are presented with a primary resistant BT leprosy. Diagnosis was made on a clinical base: luck of improvement under supervised sulfone treatment and quick regression of the lesions under a short course of rifampicine (8 weekly doses). The two children lived together with their lepromatous mothers who are suspected of DDS resistance. Where secondary DDS resistance is found only in multibacillary leprosy, primary resistance shows up in all clinical forms of leprosy.

PY - 1982 SP - 181 EP - 3 T2 - Acta leprologica TI - [2 cases of paucibacillary leprosy resistant to dapsone]. SN - 0001-5938 ER -